Angiotensin Receptor
Angiotensin receptors are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in the renin-angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone, angiotensin II. The AT1 and AT2 receptors have a similar affinity for angiotensin II, which is their main ligand. The AT1 receptor is the best elucidated angiotensin receptor. AT2 receptors are more plentiful in the fetus and neonate. Other poorly characterized subtypes include the AT3 and AT4 receptors.
Angiotensin Receptor Isoform Specific Products
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Angiotensin Receptor Inhibitors
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Angiotensin Receptor Agonists
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Angiotensin Receptor Antagonists
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Angiotensin Receptor Activators
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Angiotensin Receptor Modulators
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Angiotensin Receptor Chemicals
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Angiotensin Receptor Ligands
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Angiotensin Receptor Related Products (300)
Related Products (300)
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Antibodies (7)
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Angiotensin Receptor Isoform Comparison
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YM-358 hydrate potassium
0 ImagesCat. No.: HY-105011ACAS No.: 161800-08-4YM-358 hydrate potassium is an orally active angiotensin II type 1 (AT1)-receptor antagonist. YM-358 hydrate potassium can decrease cardiac volume overload. YM-358 hydrate potassium can be used for the research of cardiovascular disease, such as hypertension.
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Azilsartan mepixetil potassium
0 ImagesCat. No.: HY-145552ACAS No.: 2153458-32-1Synonyms: QR-01019KAzilsartan mepixetil potassium (QR-01019K) is the antagonist of angiotensin II receptor. Azilsartan mepixetil potassium has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil potassium has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A).
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LY 301875
0 ImagesCat. No.: HY-105440CAS No.: 154668-27-6LY 301875 is a potent and orally active angiotensin II receptor type 1 (AT1) antagonist with a pKB value of 9.6.
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Renin substrate, angiotensinogen (1-14), rat
0 ImagesCat. No.: HY-P5385CAS No.: 110200-37-8Renin substrate, angiotensinogen (1-14), rat is a biological active peptide. (This peptide is derived from rat angiotensinogen amino acid residues 1-14. It is a synthetic renin substrate.)
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Angiotensinogen (1-13) (human)
0 ImagesCat. No.: HY-P5939CAS No.: 82048-97-3Angiotensinogen (1-13) (human) is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides.
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H-77
0 ImagesCat. No.: HY-P2647CAS No.: 82131-82-6H-77 is a selective Renin inhibitor with an IC50 of 1.2 μM. H-77 causes dose-dependent decreases in plasma angiotensin I, plasma angiotensin II, and mean arterial pressure in sodium-depleted conscious beagle dogs. H-77 does not alter blood pressure or plasma angiotensin II levels in conscious chronically cannulated rats. H-77 can be used in studies related to the physiological and pathological states of the renin-angiotensin system.
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L-158809
0 ImagesCat. No.: HY-114586CAS No.: 133240-46-7L-158809 is an angiotensin type 1 (AT1) receptor antagonist that prevents or ameliorates fractionated whole-brain irradiation-induced cognitive impairment. L-158809 is promising for research of brain tumor.
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Tolmesoxide
0 ImagesCat. No.: HY-107037CAS No.: 38452-29-8Synonyms: RX71107Tolmesoxide (RX71107) is a peripheral vascular dilator with blood pressure lowering activity. Tolmesoxide has shown direct vasodilation in the human forearm arterial bed and dorsal hand vein. Tolmesoxide can dose-dependently increase blood flow in the forearm and produce dilation during contraction of the dorsal hand veins. Tolmesoxide can be used to study high blood pressure and angina.
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Embusartan
0 ImagesCat. No.: HY-121313CAS No.: 156001-18-2Synonyms: BAY 10-6734Embusartan (BAY 10-6734) is a brain-penetrant and effective AT1 receptor blocker. Embusartan inhibits Ang II binding to brain AT1 receptors in the nuclei of central nervous system (CNS) inside due to high lipophilic character. Embusartan is promising for research of sympathetic hyperactivity and hypertension.
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1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
![1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone](https://file.medchemexpress.com/product_pic/hy-n9530.gif "Click to View 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone Product Detail")
0 ImagesCat. No.: HY-N9530CAS No.: 120693-53-01-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC50s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL.
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BMS 183920
0 ImagesCat. No.: HY-120134CAS No.: 153072-33-4BMS 183920 is a diacidic and potent angiotensin II receptor antagonist, with a Ki value of 2.9 nM in the rat adrenal cortex binding assay and a KB value of 0.061 nM in the rabbit aorta functional assay. BMS 183920 can be used for research of antihypertensive.
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Brain Natriuretic Peptide (1-32), rat
0 ImagesCat. No.: HY-P1519CAS No.: 133448-20-1Synonyms: BNP (1-32), ratBrain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).
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EXP-6803
0 ImagesCat. No.: HY-10382CAS No.: 114773-44-3EXP-6803 is a specific nonpeptide angiotensin II receptor antagonist with antihypertensive activity. EXP-6803 inhibits the contractile response to angiotensin II with a pA2 value of 7.20. EXP-6803 effectively blocks responses to angiotensin I and II while not affecting responses to bradykinin or acetylcholine in guinea pig ileum. EXP-6803 can be used for hypertension research.
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L 681176
0 ImagesCat. No.: HY-119025CAS No.: 91386-17-3L 681176 is an angiotensin-converting enzyme inhibitor that can be isolated from STREPTOMYCES sp. MA 5143a.
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Evazarsen sodium
0 ImagesCat. No.: HY-147267ACAS No.: 2589926-24-7Synonyms: ISIS-757456 sodiumEvazarsen sodium is an angiotensinogen synthesis inhibitor and possesses antihypertensive properties.
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Tonlamarsen
0 ImagesCat. No.: HY-147406CAS No.: 2589926-20-3Synonyms: ION-904Tonlamarsen (ION-904) is a GalNAc-conjugated antisense oligonucleotide and Angiotensinogen synthesis inhibitor. Tonlamarsen specifically reduces the production of Angiotensinogen in the liver and plasma, and exhibits extremely low activity in the kidneys. Tonlamarsen can be used in research related to hypertension and heart failure.
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Sparsentan-d5
0 ImagesCat. No.: HY-17621SCAS No.: 1801597-09-0Synonyms: RE-021-d5; DARA-a-d5Sparsentan-d5 is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively.
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Angiotensin (1-12) (human)
0 ImagesCat. No.: HY-P4891CAS No.: 136865-09-3Angiotensin (1-12) (human) is an endogenous substrate for the production of biologically active angiotensin peptides by a non-renin-dependent mechanism.
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Eprosartan-d6
0 ImagesCat. No.: HY-117743S1Synonyms: SKF-108566J free base-d6Eprosartan-d6 is deuterated labeled Eprosartan (HY-117743). Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively .
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Angiotensin II (3-8), human
0 ImagesCat. No.: HY-P1515CAS No.: 12676-15-2Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.
